Series of Cardiology Research

Series of Cardiology research

Research Article

Obesity in Relationship with Different Forms of Myocardial Infarction (Data of Registry on Acute Myocardial Infarction)

Anvarovna NG

Obesity in Relationship with Different Forms of Myocardial Infarction (Data of Registry on Acute Myocardial Infarction) Read More »

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Anvarovna NG. Obesity in relationship with different forms of myocardial infarction (data of registry on acute myocardial infarction). Series Cardiol Res. 2020;2(1):10-17.
In today's world, the growth of technical progress has increased the number of people with obesity, which is one of the main risk factors for the development of acute myocardial infarction (MI). Objective: To evaluate the effect of obesity on some clinical and anthropometric characteristics in patients with acute MI. Material and Methods: A special questionnaire - a “registry card” was developed for monitoring patients with acute MI and collecting the necessary and complete information from employees of the Cardiovascular Diseases (CVD) Prevention Department. The presented article describes the data of a preliminary analysis of patients with acute MI treated in the clinic. Of the 202 people, 191 (94.6%) had a body mass index (BMI) calculated. Depending on the level of BMI, three groups were selected: 1 g (BMI < 25 kg/m2) - 36 (18.8% of 191) patients with acute MI with normal weight (control group); 2 g (BMI = 25–30 kg/m2) - 84 (44.0% of 191) overweight people; 3 g (BMI > 30 kg/m2) - 71 (37.2% of 191) people with obesity. Differences were considered significant at p < 0.05. Results: Despite the fact that acute MI developed in women 2.6 times less frequently and 8.7 years later in age than in men, nevertheless, obesity in women was recorded more often, while in men overweight prevailed. In acute MI between the age of the respondents and the presence of increased weight, an inverse relationship was revealed (p > 0.05), i.e., as the weight category increased, the age of the patients decreased. In patients with MI, as the weight increased, there was an increase in comorbid pathology, especially associated with impaired carbohydrate metabolism (p < 0.0001). A more severe form of MI (STEMI) was more often recorded in persons with a BMI > 25 kg/m2, while the front wall was the most vulnerable to the development of acute MI, regardless of the weight category of patients. The back wall was involved in the pathological process both in individuals with overweight and in patients with obesity. The apical segment in the largest number of cases was only affected in people with obesity. Conclusion: Obesity is a kind of epidemic of modern society. Its effects on the quality of life, prognosis, and effectiveness of conservative or minimally invasive treatment methods in patients with acute cardiovascular catastrophes, such as acute MI, are still a very controversial issue that requires furthermore in-depth study and analysis.
Article DOI: 10.54178/2768-5985.2020a3
Original Research

Non-ST-Elevation Acute Coronary Syndrome and Predictors of Severity Coronary Artery Disease at the Oran University Hospital Center (Algeria)

Boukerche F, Ali AA*, and Hammou L

Non-ST-Elevation Acute Coronary Syndrome and Predictors of Severity Coronary Artery Disease at the Oran University Hospital Center (Algeria) Read More »

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Boukerche F, Ali AA, Hammou L. Non-ST-Elevation Acute Coronary Syndrome and Predictors of Severity Coronary Artery Disease at the Oran University Hospital Center (Algeria). Series Cardiol Res. 2020;2(1):3-9.
Introduction: Non-ST-elevation (NSTE) acute coronary syndrome (ACS) is a common and polymorphic condition. Predicting significant coronary artery disease (CAD) is sometimes difficult. The objective of this study was to identify predictors of CAD severity in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). Patients and Methods: We prospectively evaluated 296 patients with NSTE-ACS who underwent a coronary angiography. Significant CAD was defined as ≥70% stenosis in at least one major coronary artery. Clinical characteristics in the hospital for 30 days and one-year outcomes were prospectively noted and a multivariate analysis was performed.Results: The study included 296 NSTE-ACS patients. The mean age of the patients was 62.1 ± 12.6 years old while 58.1% of the patients were males. A  multivariable analysis for the significant CAD predictors is shown (Figure 1), representing current smoking (ORa = 4.4; 95% confidence interval [CI] = 1.5–13.0, p = 0.007), a diabetic under insulin (Ora = 6.4; 95% [CI] = 2.4–17.4, p < 10-3), typical angina (ORa = 5.4; 95% [CI] = 1.7–16.8, p = 0.003),  persistent angina (ORa = 5.3; 95% [CI] = 1.3–21.8, p = 0.019), recurrence of angina (ORa = 8.9; 95% [CI] = 1.5–51.4; p = 0.015), down sloping ST depression (ORa = 6.1; 95% [CI] = 2.4–15.3, p < 10-3), positive troponin (ORa = 4.2; 95% [CI] = 1.9–9.2, p < 10-3), kinetic disorder > 2 segments (ORa = 2.5; 95% [CI] = 1.1–6.0, p = 0.049), intima-media thickness (IMT) > 0.8 mm (ORa = 5.2; 95% [CI] = 2.3–12.1, p < 10-3). Conclusion: In this study, the severity of CAD was predicted by parameters such as typical or recurrent angina pectoris, current smoking, diabetic on insulin, down sloping ST depression, elevation of troponin, kinetic anomaly in more than two segments and the IMT greater than 0.8 mm.
Article DOI: 10.54178/2768-5985.2020a2
Research Article

Contribution of Transesophageal Echocardiography in the Etiological Diagnosis of Ischemic Stroke: Retrospective Study of 56 Cases

Ndiaye MB, Mingou JS*, Sarr SA, Aw F, Thiam A, Bodian M, Mbaye A, Kane Ad, Diao M, Kane A and Ba SA

Contribution of Transesophageal Echocardiography in the Etiological Diagnosis of Ischemic Stroke: Retrospective Study of 56 Cases Read More »

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Ndiaye MB, Mingou JS, Sarr SA, et al. Contribution of transesophageal echocardiography in the etiological diagnosis of ischemic stroke: retrospective study of 56 cases. Series Cardiol Res. 2019;1(1):4-10.
Introduction: Strokes constitute a public health problem. Ischemic strokes are caused by cardioembolic diseases in 20% of cases. We have realized this study in order to situate the role of transesophageal echocardiography in the search of cardioembolic diseases during ischemic strokes. Materials and Methods: We have realized a retrospective study in the Cardiology Department of “Hopital Général de Grand Yoff” at Dakar, during two years from June 2003 to July 2005. Our patients received benefits from medical examination, biological exams, an ECG, a recording ECG, a transesophageal echocardiography, transthoracic echocardiography, a brain scan and echodoppler of neck vessels. Results: Fifty-six cases have been identified. The average age was of 60.3 ± 14.3 years (extremes: 21–87 years). The sex-ratio (men over women) was of 0.75. The cardiovascular risk factors were dominated by blood hypertension and diabetes. On the standard electrocardiogram, we noted eleven cases of atrial fibrillation and one case of atrial flutter. Two patients have presented a paroxystic atrial fibrillation on recording electrocardiogram and six (10.7%), either a significative stenosis or carotid thrombosis at neck vessels echodoppler. The board number V is the summery of the etiology of ischemic strokes found by transesophageal echocardiography.
Article DOI: 10.54178/2768-5985.2019a1
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