Bacterial keratitis is a serious and potentially sight-threatening complication most commonly associated with overnight contact lens wear. This case report presents the management of a 22-year-old male patient who developed bacterial keratitis following non-compliance with recommended contact lens care practices, specifically sleeping in contact lenses. The report discusses the diagnosis, differential diagnosis, and treatment, along with the risk factors associated with contact-lens-related microbial keratitis (CLMK). Early intervention with fortified antibiotics and patient education led to a quick resolution of the condition. This case emphasizes the importance of proper contact lens hygiene and the timely treatment of bacterial keratitis to prevent visual impairment.