Series of Surgery and Intensive Care Medicine

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Research Article

First Postnatal Ultrasound Scan to Predict the Outcome of Antenatally Diagnosed Hydronephrosis

Zia BB, Lisseter R, Niyogi A, Gopal M and Godse A*

First Postnatal Ultrasound Scan to Predict the Outcome of Antenatally Diagnosed Hydronephrosis Read More »

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Zia BB, Lisseter R, Niyogi A, et al. First postnatal ultrasound scan to predict the outcome of antenatally diagnosed hydronephrosis. Series Surg Intensive Care Med. 2025;1(1):1-9.
Purpose: To determine if anteroposterior renal pelvic diameter (APD) on the first postnatal ultrasound (US) scan can predict outcomes in children with antenatal hydronephrosis (ANH). Method: Data on all babies with ANH born in our center from 2009–2015 was obtained from the National Congenital Anomaly and Rare Disease Registration Service (NCARDRS). The medical records were reviewed. Statistical analysis was performed on GraphPad. Results: 223 babies were included in the study. 165 (74%) had spontaneous resolution of hydronephrosis. The mean APD on the first US was 13.3 mm in children whose ANH was resolved and 25.3 mm in those with persistent ANH (p < 0.01). 50 procedures were performed on 37 children. The most common procedure was pyeloplasty (n = 15), followed by total or partial nephroureterectomy (n = 12). 21 children had persistent dilatation but needed no intervention. Renal duplex (n = 8) was the most common diagnosis in this group (persistent dilatation) followed by vesicoureteric reflux (VUR) (n = 7). All babies with APD > 24 mm on their first US required surgical intervention. Conclusion: While most ANH resolves spontaneously, children with higher APD in the first US have a higher likelihood of subsequent surgery. All children with APD > 24 mm require surgery. This information is beneficial in postnatal counseling for children with ANH.
Research Article

Congenital Diaphragmatic Hernia (CDH) Needing Extracorporeal Membrane Oxygenation (ECMO): Early and Long-Term Outcomes of a High-Volume Tertiary Referral Hospital Over 21 Years

Zia BB, Paraboschi I, Thiruchelvam T, Muthialu N, Cross K, De Coppi P, Curry JI, Loukogeorgakis S, Mullaserry D, Blackburn S and Giuliani S*

Congenital Diaphragmatic Hernia (CDH) Needing Extracorporeal Membrane Oxygenation (ECMO): Early and Long-Term Outcomes of a High-Volume Tertiary Referral Hospital Over 21 Years Read More »

Abstract Full TextPDF Cite
Zia BB, Paraboschi I, Thiruchelvam T, et al. Congenital diaphragmatic hernia (CDH) needing extracorporeal membrane oxygenation (ECMO): early and long-term outcomes of a high-volume tertiary referral hospital over 21 years. Series Surg Intensive Care Med. 2025;1(1):1-13.
Introduction: We present early and long-term outcomes of infants born with congenital diaphragmatic hernia (CDH) who received extracorporeal membrane oxygenation (ECMO). Materials and Methods:CDH neonates treated with ECMO from 1st January 2000 to 31st December 2021 were included. Demographics and postnatal data were obtained. 1-year and long-term outcomes were: mortality, length of hospital stay (LOS), recurrence, readmission, ECMO-related adverse events, and surgical complications. Median, interquartile range, and percentages were used. Institutional audit registration (IR3952). Results: 58/392 (14.8%) patients received ECMO. 25/58 (43.1%) were female. Median birth weight was 2.92 kg (IQR 2.760 - 3.230). 47/58 (81.0%) neonates underwent surgical repair of the diaphragmatic defect (thoracoscopic, n = 6, 12.7%; open repair, n = 41, 87.2%). 42/47 (89.3%) patients were repaired within a median of 144 h (IQR 80 - 270) after ECMO decannulation. 37/47 (78.7%) patients survived after the surgical repair and were discharged home at a median of 33 days (IQR: 16 - 37) after surgery. At 1 year the outcomes were: 1 death from persistent pulmonary hypertension at 5 months after discharge, total re-admissions were 16/37 (43.2%), hernia recurrence in 2 (5.4%) infants, feeding difficulties secondary to gastroesophageal reflux in 4 (10.8%) children, and 2 (5.4%) required a Nissen fundoplication. Long-term follow-up duration after initial hospital discharge was 7.2 years (IQR 6.5 - 9.8).
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