Series of Medical Science​

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Research Article

Factors Responsible for Prevalence of Cardiovascular Disease Among Patients with Elevated Blood Pressure

Belal AA

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Belal AA. Factors responsible for prevalence of cardiovascular disease among patients with elevated blood pressure. Series Med Sci. 2024;5(1):1-10.
In this paper, an attempt was made to identify the risk factors associated with the prevalence of cardiovascular disease (CVD) in Bangladeshi patients with elevated blood pressure. The patients were observed in investigating 995 adults of 18 years and above. The data of these adults were collected from some diagnostic centers located in urban and semi-urban areas when the adults were visiting the centers for their blood and urine screening tests. Among the investigated adults, 452 were patients with elevated blood pressure; 39 of these patients were suffering from CVD. The objective of the study was to identify some socioeconomic factors for the simultaneous prevalence of the diseases among the group of 39 patients. The risk of these two non-communicable diseases was significantly higher for younger adults, for physically inactive adults, and for diabetic patients of early stages. Higher risk was also noted for non-Muslim people, females, secondary educated persons, housewives, adults belonging to families of upper medium economic condition, processed food consumers, and underweight adults. The patients’ group was well discriminated from others for the variables age, habit of doing physical work, and economic condition.
Review Article

Harnessing the Antileishmanial Potential of Medicinal Plants

Mohebbi A, Masoudiankhouzani M, Pirhadi R, Rezaee F and Dinari N*

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Mohebbi A, Masoudiankhouzani M, Pirhadi R, et al. Harnessing the antileishmanial potential of medicinal plants. Series Med Sci. 2024;5(1):1-15.
Leishmaniasis, a disease caused by various species of the Leishmania parasite and primarily transmitted by female sandflies, poses a significant health concern in tropical and subtropical regions. This review explores recent advancements in understanding the disease, its transmission, and available treatment options. Despite the availability of treatment options such as pentavalent antimony, including sodium stibogluconate and meglumine antimoniate, their efficacy is compromised by severe side effects and the emergence of resistant parasites. The necessity for alternative therapeutics has increased interest in plant-derived compounds with anti-parasitic properties. Notable examples include Artemisia annua, Peschiera australis, Piper aduncum, and Physalis angulata, which have demonstrated promising efficacy against Leishmania parasites. However, developing effective treatments faces challenges, including the need for more stable and potent drugs. While medicinal plants offer potential solutions, their use requires caution due to possible adverse effects and interactions, particularly in vulnerable populations like children and pregnant women. Nevertheless, medicinal plants continue to be explored as valuable resources for developing safe and cost-effective treatments for leishmaniasis. In conclusion, there is an urgent need for novel therapeutic approaches to combat leishmaniasis, highlighting the potential of medicinal plants as sources of effective anti-parasitic agents.
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